Cystic nephroma : a diagnostic dilemma

• Published in: Saudi journal of kidney diseases and transplantation Vol. 21; no. 3; pp. 518 - 520
• Main Authors: Gupta, Arun, Mohanty, Debajyoti, Jain, Bhupendra Kumar, Agrawal, Vivek
• Format: Journal Article
• Language: English
• Published: Riyadh, Saudi Arabia Saudi Center for Organ Transplantation 01.05.2010; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Adult; Biopsy; Care and treatment; Case studies; Cholecystectomy; CT imaging; Diagnosis; Female; Health aspects; Humans; Kidney - diagnostic imaging; Kidney - pathology; Kidney - surgery; Kidney Neoplasms - diagnosis; Kidney Neoplasms - surgery; Kidneys; Middle Aged; Nephrectomy; Nephroblastoma; Nephroma, Mesoblastic - diagnosis; Nephroma, Mesoblastic - surgery; Patient outcomes; Predictive Value of Tests; Radiography; Risk factors; Treatment Outcome; Tumors; Urine - cytology; الأورام; الأورام الحميدة; التشخيص; الكلى; المرضى; علم المداواة; Saudi Arabia
• ISSN: 1319-2442; 2320-3838

Cystic nephroma (CN) is a rare benign neoplasm of kidney with excellent prog­nosis. An accurate pre-operative diagnosis differentiating CN from other cystic renal malignan­cies may be impossible by clinical and radiological examination, and histopathological exami­nation provides the final diagnosis. This report describes two adult patients with large multi-locular cystic renal masses on imaging and the diagnosis of CN was clinched post-operatively by the ho­neycomb appearance of the cut specimen and the finding of multiple, non-communicating fluid filled cysts lined by cuboidal or flattened epithelial cells and absence of blastemal cells on mic­roscopy. Tumor diameter on cross sectional imaging remains the key parameter for treatment de­cisions in renal neoplasms, with nephrectomy being preferred for larger lesions.