Reproductive technologies needed for the generation of precise gene-edited pigs in the pathways from laboratory to farm

Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic...

Full description

Saved in:
Bibliographic Details
Published inAnimal Bioscience Vol. 36; no. 2 SI; pp. 339 - 349
Main Authors Tu, Ching-Fu, Peng, Shu-Hui, Chuang, Chin-kai, Wong, Chi-Hong, Yang, Tien-Shuh
Format Journal Article
LanguageEnglish
Published Asian - Australasian Association of Animal Production Societies 01.02.2023
Animal Bioscience
Asian-Australasian Association of Animal Production Societies
아세아·태평양축산학회
Subjects
Agricultural research
Agriculture
Animal culture
Animal genetic engineering
Breeding
Embryonic development
farm
Farms
gene-editing
Genetically modified animals
Invited Review
Methods
new breeding technique
Physiological aspects
pigs
reproductive biotechnology
Reproductive technology
Stem cells
sustainability
Swine
축산학
Taiwan
Online AccessGet full text

Cover

More Information
Summary:Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic cell nuclear transfer, cryopreservation, and nonsurgical embryo transfer. The extension of NBT in the new era of pig breeding depends on the synergistic effect of GE and reproductive biotechnologies; the outcome relies not only on scientific due diligence and operational excellence but also on the feasibility of application on farms to improve sustainability.
ISSN:2765-0235
2765-0189
2765-0235
DOI:10.5713/ab.22.0389