Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014-2018

Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift...

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Published inEmerging infectious diseases Vol. 25; no. 10; pp. 1932 - 1935
Main Authors Bai, Ru, Sikkema, Reina S, Li, Cong Rong, Munnink, Bas B Oude, Wu, Jie, Zou, Lirong, Jing, Yi, Lu, Jing, Yuan, Runyu, Liao, Ming, Koopmans, Marion P G, Ke, Chang-Wen
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.10.2019
Centers for Disease Control and Prevention
Subjects
Animals
Antibodies
Antigenic variation
Antigens, Viral - genetics
Antigens, Viral - immunology
Avian influenza
Chickens - virology
China
China - epidemiology
Ducks
Geese
Genetic Drift
Guangdong Province
H5N6
Health aspects
Infection
Influenza
Influenza A virus - genetics
Influenza A virus - immunology
Influenza in Birds - epidemiology
Influenza in Birds - genetics
Influenza in Birds - immunology
Influenza in Birds - virology
Influenza vaccines
Phylogeny
Poultry Diseases - epidemiology
Poultry Diseases - immunology
Poultry Diseases - virology
Real-Time Polymerase Chain Reaction - veterinary
Resveratrol
Reverse Transcriptase Polymerase Chain Reaction - veterinary
Vaccination
zoonosis
China
chickens
poultry
viruses
avian influenza
Guangdong Province
H5N6
live poultry markets
Antigenic variation
China
zoonoses
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Abstract Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.
AbstractList Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.
Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014–2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.
Audience Professional
Academic
Author Koopmans, Marion P G
Sikkema, Reina S
Yuan, Runyu
Wu, Jie
Li, Cong Rong
Liao, Ming
Jing, Yi
Ke, Chang-Wen
Lu, Jing
Zou, Lirong
Munnink, Bas B Oude
Bai, Ru
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Issue 10
Keywords chickens
poultry
viruses
avian influenza
Guangdong Province
H5N6
live poultry markets
Antigenic variation
China
zoonoses
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SubjectTerms Animals
Antibodies
Antigenic variation
Antigens, Viral - genetics
Antigens, Viral - immunology
Avian influenza
Chickens - virology
China
China - epidemiology
Ducks
Geese
Genetic Drift
Guangdong Province
H5N6
Health aspects
Infection
Influenza
Influenza A virus - genetics
Influenza A virus - immunology
Influenza in Birds - epidemiology
Influenza in Birds - genetics
Influenza in Birds - immunology
Influenza in Birds - virology
Influenza vaccines
Phylogeny
Poultry Diseases - epidemiology
Poultry Diseases - immunology
Poultry Diseases - virology
Real-Time Polymerase Chain Reaction - veterinary
Resveratrol
Reverse Transcriptase Polymerase Chain Reaction - veterinary
Vaccination
zoonosis
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Title Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014-2018
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