Preparation of self-preserving personal care cosmetic products using multifunctional ingredients and other cosmetic ingredients

• Published in: Scientific reports Vol. 14; no. 1; pp. 19401 - 10
• Main Authors: Senthilkumar, K., Vijayalakshmi, A., Jagadeesan, Manjunathan, Somasundaram, Ambiga, Pitchiah, Sivaperumal, Gowri, S. Shyamala, Ali Alharbi, Sulaiman, Javed Ansari, Mohammad, Ramasamy, Pasiyappazham
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.08.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/45; 692/700; Acids; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Chlorides; Conventional preservatives; Cosmetics; Cosmetics - chemistry; Cosmetics industry; Fatty Acids, Monounsaturated - chemistry; Humanities and Social Sciences; Humans; Ketones; Microbial Sensitivity Tests; Minimum inhibitory concentration; multidisciplinary; Multifunctional ingredients; Palmitoleic acid; Personal care formulations; Personal grooming; Preservation; Preservatives; Ricinoleic acid; Science; Science (multidisciplinary); Self-preservatives; Shampoos; Skin tests; Sodium; Sorbitan; Synergy; Multifunctional ingredients; Cosmetics; Personal care formulations; Conventional preservatives; Synergy; Self-preservatives
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-57782-9

The development of self-preserving personal care cosmetics represents a significant advancement in the cosmetics industry, offering safer and more natural alternatives to consumers. This study focused on the preparation of such formulations using multifunctional ingredients along with other cosmetic components. Five unique multifunctional ingredients (MFIs) were identified based on their antimicrobial properties: sodium coco PG-dimonium chloride phosphate, ricinoleic acid, palmitoleic acid, raspberry ketone, and sorbitan caprylate. Through meticulous experimentation, 150 combinations of MFIs were prepared and tested to understand their synergistic actions. From these trials, three synergistic antimicrobial compositions were determined: sodium coco PG-dimonium chloride phosphate: ricinoleic acid: raspberry ketone in the ratios 1:6.3:6.3 and 1:6.3:15.7. Sodium coco PG-dimonium chloride phosphate: palmitoleic acid: sorbitan caprylate at a ratio of 1:12.5:37.5. These synergistic compositions exhibited enhanced antimicrobial efficacy compared with their individual components, as evidenced by their lower Minimum Inhibitory Concentration values. Incorporating these formulations into three distinct personal care cosmetic products, including a color protection shampoo, body wash shower gel, and skin-lightening cream, the study further validated their effectiveness. A Preservation Challenge Test study revealed that all three antimicrobial compositions successfully preserved the cosmetic formulations for up to 28 days. This method of product preservation not only ensures consumer safety and stability but also reduces the need for potentially conventional preservatives. In conclusion, the appropriate use of multifunctional ingredients in combination with meticulous formulation techniques has led to the successful development of self-preserving personal care cosmetics. These formulations offer a promising avenue for the cosmetic industry, catering to the rising demand for natural, effective, and consumer-friendly cosmetic products.