Biological Applications of Thiourea Derivatives: Detailed Review

Thiourea and its derivatives have become a significant focal point within the organic synthesis field, garnering attention for their diverse biological applications, including antibacterial, antioxidant, anticancer, anti-inflammatory, anti-Alzheimer, antituberculosis and antimalarial properties. My...

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Bibliographic Details
Published inChemistry an international journal Vol. 6; no. 3; pp. 435 - 468
Main Author Agili, Fatimah A
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.06.2024
Subjects
anti-Alzheimer
anti-inflammatory
antibacterial
Antibiotics
anticancer
Antimicrobial agents
antioxidant
Antioxidants
E coli
Ligands
Ovarian cancer
Potassium
Sulfur
thiourea
Thiourea derivatives
Toxicity
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Summary:Thiourea and its derivatives have become a significant focal point within the organic synthesis field, garnering attention for their diverse biological applications, including antibacterial, antioxidant, anticancer, anti-inflammatory, anti-Alzheimer, antituberculosis and antimalarial properties. My objective is to present a comprehensive and easily understandable analysis of recent advancements in the organic synthesis of thiourea derivatives. My focus is on the structure and activity of these derivatives over the past five years, highlighting the significant progress made in the field of organic synthesis. Additionally, I evaluate the current state of research in this area and provide an overview of the latest trends and future prospects. This review will prove to be beneficial for researchers, academics and industry professionals involved in drug development and organic synthesis.
ISSN:2624-8549
DOI:10.3390/chemistry6030025