Antinociceptive action of Vanillosmopsis arborea in male mice

Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of Baker (EOVA) in mice. The antinociceptive activity was...

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Published inAvicenna journal of phytomedicine Vol. 7; no. 1; pp. 93 - 98
Main Authors Leite, Laura Inocencio, Leite, Gerlânia de Oliveira, Fernandes Silva, Bruno Anderson, Gonçalves Sousa, Severino Denício, Coutinho, Thales Silva, Sampaio, Renata Souza, Menezes, Irwin, Martins Costa, José Galberto, Campos, Adriana Rolim
Format Journal Article
LanguageEnglish
Published Iran Mashhad University of Medical Sciences 01.01.2017
Subjects
Antinociceptive
Antipruritic
Essential oil
Original
Vanillosmopsis arborea
Antinociceptive
Essential oil
Vanillosmopsisarborea
Antipruritic
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Summary:Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of Baker (EOVA) in mice. The antinociceptive activity was assessed using the capsaicin, glutamate, hot plate and cold allodynia tests. The antipuritic effects were also verified based on histamine-induced scratching behavior. EOVA reduced the paw licking induced by capsaicin, but not that induced by glutamate. The essential oil increased the latency time in the hot plate, attenuated the cold allodynia induced by acetone and inhibited histamine-induced scratching behavior. The experimental data demonstrated that EOVA showed central and peripheral antinociceptive activity and antipruritic effect.
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ISSN:2228-7930
2228-7949
DOI:10.22038/ajp.2016.6956