Electrical storms in Brugada syndrome: review of pharmacologic and ablative therapeutic options

Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in preventing multiple recurrences of ventricula...

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Published inIndian pacing and electrophysiology journal Vol. 5; no. 1; pp. 25 - 34
Main Authors Maury, P, Hocini, M, Haïssaguerre, M
Format Journal Article
LanguageEnglish
Published Netherlands Indian Pacing and Electrophysiology Group 01.01.2005
Elsevier
Subjects
ablation
Brugada syndrome
electrical storm
isoproterenol
quinidine
Reviews
ventricular fibrillation
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Summary:Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in preventing multiple recurrences of ventricular arrhythmias. Isoproterenol should be immediately infused while oral quinidine should be further administrated when isoproterenol is not effective. In case of failure of these therapeutic options, ablation of the triggering ventricular ectopies should be attempted.
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ISSN:0972-6292
0972-6292