Two new Cd(II)/Co(II) compounds: Luminescent and photocatalytic property, and treatment activity on coronary artery atherosclerosis

Two new compounds, namely [Cd2(L)2(4-pybim)2(H2O)]n·3n(H2O) (1) and [Co(cam)(4-pybim)]n·n(H2O) (2) (H2L = succinic acid, H2cam = D-(+)-camphoric acid, 4-pybim = (4-pyridyl)benzimidazole), were successfully synthesized by the combination of carboxylate ligand, 4-pybim ligand and corresponding metal s...

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Bibliographic Details
Published inArabian journal of chemistry Vol. 15; no. 1; p. 103498
Main Authors Hai-Bo Yu, Feng-Jiang Chen, Jing Li, Yu-Ming Kang, Yan-Kun Zhang, Yuan Shan
Format Journal Article
LanguageEnglish
Published Elsevier 01.01.2022
Subjects
Coronary artery atherosclerosis
Luminescence
Photocatalysis
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Summary:Two new compounds, namely [Cd2(L)2(4-pybim)2(H2O)]n·3n(H2O) (1) and [Co(cam)(4-pybim)]n·n(H2O) (2) (H2L = succinic acid, H2cam = D-(+)-camphoric acid, 4-pybim = (4-pyridyl)benzimidazole), were successfully synthesized by the combination of carboxylate ligand, 4-pybim ligand and corresponding metal salts. Moreover, the luminescent property of 1 and photocatalytic activity of 2 were also investigated in detail. The application values of the new compounds against coronary artery atherosclerosis were evaluated and the detail mechanism was assessed simultaneously. First of all, the inflammatory cytokines levels released into plasma after compound treatment was measured with the detection of enzyme-linked immunosorbent assay. Then, the relative expression of the signaling pathway of NF-κb in the vascular endothelial cells was tested through exploiting the real time reverse transcription-polymerase.
ISSN:1878-5352
DOI:10.1016/j.arabjc.2021.103498