The case of the “serfdom” condition of phagocytic immune cells

In a modern immunological perspective, it may be asserted that the phagocytic cell should not be considered as the "serfdom", but rather the pivot of the immune system. Indeed, the invertebrate immunocyte as well as the vertebrate macrophage play a central role in immunity, inflammation an...

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Bibliographic Details
Published inInvertebrate survival journal Vol. 9; no. 2; pp. 134 - 138
Main Authors E Ottaviani, D Malagoli, A Grimaldi, M de Eguileor
Format Journal Article
LanguageEnglish
Published University of Modena and Reggio Emilia 01.01.2012
Subjects
evolution
immune and neuroendocrine responses
invertebrate immunocyte
vertebrate macrophage
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Summary:In a modern immunological perspective, it may be asserted that the phagocytic cell should not be considered as the "serfdom", but rather the pivot of the immune system. Indeed, the invertebrate immunocyte as well as the vertebrate macrophage play a central role in immunity, inflammation and stress response. The evolutionary conserved immune-neuroendocrine effector system have remained of fundamental importance in defense against pathogens, and its efficiency increased through synergy with the new, clonotipical recognition repertoire in vertebrates.
ISSN:1824-307X
1824-307X