Changes in Serum Acute Phase Reactants, Inflammatory Mediators and Gangliosides in Japanese quail (Coturnix japonica) with Retained Yolk Sac

Twenty-two 2-week-old Japanese quails (Coturnix japonica) with retained yolk sac have been assessed using validated standard procedures to quantify the serum concentration of the acute phase reactants (haptoglobin and serum amyloid A), inflammatory mediators (tumor necrosis factor-alpha, gamma inter...

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Bibliographic Details
Published inPakistan veterinary journal Vol. 32; no. 2; pp. 251 - 254
Main Author N. Mosleh, S. Nazifi and A. Alaeddini
Format Journal Article
LanguageEnglish
Published University of Agriculture, Faisalabad 01.01.2012
Subjects
Acute phase reactants
Gamma interferon
Gangliosides
Japanese quail
Tumor necrosis factor-alpha
Yolk sac retention
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Summary:Twenty-two 2-week-old Japanese quails (Coturnix japonica) with retained yolk sac have been assessed using validated standard procedures to quantify the serum concentration of the acute phase reactants (haptoglobin and serum amyloid A), inflammatory mediators (tumor necrosis factor-alpha, gamma interferon) and gangliosides (total sialic acid, lipid bound sialic acid and protein bound sialic acid). The present findings show that the concentrations of all measured parameters in diseased birds were significantly higher than the control group. Inflammation following yolk sac infection/retention leads to stimulation of the synthesis of inflammatory mediators, acute phase reactants and gangliosides. Among the study variables, lipid bound sialic acid had the most obvious change, so it is the most sensitive parameter.
ISSN:0253-8318