Treatment Outcomes and Prognostic Factors of Pulmonary Metastasectomy for Bone and Soft Tissue Sarcoma: a High Volume Academic Institution Experience

The bone and soft tissue sarcoma can metastasize to distant sites, most commonly the lungs. Some cases can be cured by radical metastasectomy, but its role, indication and prognostic factors remains controversial. The rarity of the disease combined with the diverse number of subtypes can make bone a...

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Published inZhongguo fei ai za zhi Vol. 19; no. 5; pp. 299 - 306
Main Authors Kang, Xiaozheng, Yan, Wanpu, Yang, Yongbo, Dai, Liang, Liang, Zhen, Huang, Zhen, Niu, Xiaohui, Chen, Keneng
Format Journal Article
LanguageChinese
Published China Chinese Anti-Cancer Association Chinese Antituberculosis Association 20.05.2016
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
Subjects
Adolescent
Adult
Aged
Biopsy
Bone cancer
Bone Neoplasms - pathology
Cancer therapies
Chemotherapy
Child
Children & youth
Clinical medicine
Epidemiology
Female
Humans
Lung Neoplasms - secondary
Lung Neoplasms - surgery
Lymphatic system
Male
Medical prognosis
Metastasectomy
Metastasis
Middle Aged
Oncology
Osteosarcoma
Prognosis
Recurrence
Retrospective Studies
Sarcoma - pathology
Soft Tissue Sarcoma
Thoracic surgery
Treatment Outcome
Young Adult
Beijing China
United States > US
China
Europe
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ISSN1009-3419
1999-6187
DOI10.3779/j.issn.1009-3419.2016.05.10

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Summary:The bone and soft tissue sarcoma can metastasize to distant sites, most commonly the lungs. Some cases can be cured by radical metastasectomy, but its role, indication and prognostic factors remains controversial. The rarity of the disease combined with the diverse number of subtypes can make bone and soft tissue sarcomas very difficult to study. There are few randomized control studies or international high volume results, and such reports in China are seldom seen. The aim of this study is to investigate surgical treatment outcomes and prognostic factors of pulmonary metastatic bone and soft tissue sarcoma patients. From January 2007 to December 2015, patients with bone and soft tissue sarcoma who underwent multimodality therapy including definitive surgery for the primary lesion and at least one pulmonary metastasectomy were enrolled in the retrospective study. All the relevant clinical variables were collected, and then statistically analyzed and interpreted with the aid of univariate and multivariate Cox
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ISSN:1009-3419
1999-6187
DOI:10.3779/j.issn.1009-3419.2016.05.10