Pharmacotherapy for rheumatoid arthritis in the early 21st century: Russian and international experience

The paper summarizes the data of international and Russian studies concerning current approaches to the pharmacotherapy of rheumatoid arthritis. Particular emphasis is placed on the substantiation of the treat-to-target concept, on the efficacy and safety of genetically engineered biological agents,...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 85; no. 8; pp. 20 - 28
Main Authors Nasonov, E L, Karateev, D E, Lukina, G V
Format Journal Article
LanguageRussian
Published Russia (Federation) "Consilium Medicum" Publishing house 01.01.2013
Subjects
Arthritis, Rheumatoid - drug therapy
Arthritis, Rheumatoid - history
Arthritis, Rheumatoid - immunology
cytokines
History, 21st Century
Humans
Immunologic Factors - immunology
Immunologic Factors - therapeutic use
methotrexate
remission
rheumatoid arthritis
Rheumatology - history
Rheumatology - trends
Russia
tumor necrosis factor inhibitors
Russia
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Summary:The paper summarizes the data of international and Russian studies concerning current approaches to the pharmacotherapy of rheumatoid arthritis. Particular emphasis is placed on the substantiation of the treat-to-target concept, on the efficacy and safety of genetically engineered biological agents, including the inhibitors of tumor necrosis factor, interleukin-6 receptors, T-lymphocyte co-stimulation, and anti-B-cell therapy.
ISSN:0040-3660
2309-5342