Factors Associated With Non-Uptake of Implantable Cardioverter-Defibrillator (ICD) Among Eligible Patients at a Tertiary Hospital in Kenya

• Published in: Global heart Vol. 19; no. 1; p. 66
• Main Authors: Oluoch, Emmanuel, Shah, Jasmit, Varwani, Mohamed, Jeilan, Mohamed, Ngunga, Mzee
• Format: Journal Article
• Language: English
• Published: England Ubiquity Press 01.01.2024
• Subjects: Adult; Aged; Death, Sudden, Cardiac - epidemiology; Death, Sudden, Cardiac - prevention & control; Defibrillators, Implantable - statistics & numerical data; Female; Heart Failure - epidemiology; Heart Failure - therapy; Humans; implantable cardioverter-defibrillator (icd); Kenya - epidemiology; Male; Middle Aged; non-uptake; Primary Prevention - methods; Retrospective Studies; Stroke Volume - physiology; sub-saharan africa (ssa); Tertiary Care Centers; Kenya; non-uptake; Implantable Cardioverter-Defibrillator (ICD); Sub-Saharan Africa (SSA)
• ISSN: 2211-8179; 2211-8179
• DOI: 10.5334/gh.1346

Efficacy of Implantable Cardioverter-Defibrillator (ICD) implantation in both primary and secondary prevention of Sudden Cardiac Death (SCD) in at-risk population is well established. ICD implantation rates remain low particularly in Africa with a paucity of data regarding factors associated with non-uptake. The primary study objective was to determine the factors associated with non-uptake of ICD among heart failure (HF) patients with reduced ejection fraction (EF<35%). Reasons for ICD refusal among eligible patients were reviewed as a secondary objective. This was a retrospective study among HF patients eligible for ICD implantation evaluated between 2018 to 2020. Comparison between ICD recipient and non-recipient categories was made to establish determinants of non-uptake. Of 206 eligible patients, only 69 (33.5%) had an ICD. Factors independently associated with non-uptake were lack of private insurance (42.3% vs 63.8%; p = 0.005), non-cardiology physician (16.1% vs 5.8%; p = 0.045) and non-ischemic cardiomyopathy (54.7% vs 36.4% p = 0.014). The most common (75%) reason for ICD refusal was inability to pay for the device. ICDs are underutilized among eligible HF with reduced EF patients in Kenya. The majority of patients without ICD had no private insurance, had non-ischemic cardiomyopathy and non-cardiology primary physician. Early referral of HF with reduced EF patients to HF specialists to optimize guideline-directed medical therapy and make ICD recommendation is needed.