Maternal-fetal transmission of Trypanosoma cruzi, a health problem slightly studied in Mexico: case Chiapas

• Published in: Salud pública de México Vol. 58; no. 3; pp. 378 - 384
• Main Authors: Campos-Valdez, Guillermina, Canseco-Ávila, Luis Miguel, González-Noriega, Fernando, Alfaro-Zebadua, Oscar, Nava-Medecigo, Ismael Yadird, Jiménez-Cardoso, Enedina
• Format: Journal Article
• Language: Spanish
• Published: Mexico Instituto Nacional de Salud Pública 01.06.2016
• Subjects: Adult; Asymptomatic Diseases; Chagas Disease - epidemiology; Chagas Disease - transmission; enfermedad de Chagas; Female; Geography, Medical; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical - statistics & numerical data; Male; Mexico - epidemiology; México; Pregnancy; Pregnancy Complications, Infectious - epidemiology; Pregnancy Outcome; Seroepidemiologic Studies; Trypanosoma cruzi; Trypanosoma cruzi - immunology; Young Adult
• ISSN: 0036-3634; 1606-7916
• DOI: 10.21149/spm.v58i3.7898

To determine the Trypanosoma cruzi infection prevalence in 1125 pregnant women and the transmission frequency to their children from Tapachula and Palenque, Chiapas. We determined the prevalence by serology tests and the transmission frequency by polymerase chain reaction (PCR) and T. cruzi reactivity capacity after 12 months. Total maternal infection prevalence were 23/1 125 (2.04%), 9/600 (1.5%) were from Tapachula and 14/525 (2.6%) from Palenque. The seropositive women were between 20 and 35 years old, 31.8% have Premature Rapture of Membrane and 9.1% have history of perinatal death. The total percentage of positive newborns by PCR was 9/23 (39.13%), out of those 2/9 (22.2%) are from Tapachula and 7/14 (50%) from Palenque. The Maternal Fetal transmission frequency was. 2/9 (22.2%) in Tapachula and 1/14 (7.14%) in Palenque, all positive infants were asynthomatic. The maternal-fetal transmission rate in Chiapas State is variable; the reason could be the maternal immunological status and T. cruzi strain.