Taurin in combined treatment of metabolic syndrome and diabetes mellitus

• Published in: Terapevtic̆eskii arhiv Vol. 83; no. 10; pp. 31 - 36
• Main Authors: Aleksandr Sergeevich Ametov, Irina Ivanovna Kochergina, Elena Valer'evna Doskina, Birlant Said-Mukhamedovna Abaeva, Evgeniya Pavlovna Elizarova, A S Ametov, I I Kochergina, E V Doskina, B S-M Abaeva, E P Elizarova
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) "Consilium Medicum" Publishing house 01.01.2011
• Subjects: Comorbidity; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - epidemiology; dibicor; Humans; metabolic syndrome; Metabolic Syndrome - drug therapy; Metabolic Syndrome - epidemiology; Multicenter Studies as Topic - methods; Prevalence; Randomized Controlled Trials as Topic - methods; taurin; Taurine - therapeutic use; treatment; type 2 diabetes mellitus
• ISSN: 0040-3660; 2309-5342

In addition to information on the prevalence, etiology and pathogenesis of metabolic syndrome and type 2 diabetes mellitus, the role of insulin resistance, lipotoxicity, hyperglycemia and glucose toxicity in development complications of metabolic syndrome and diabetes mellitus, the article presents evidence from multicenter clinical trials of taurin/dibicor efficacy in the treatment of metabolic syndrome, diabetes mellitus, cardiovascular complications, diabetic retinopathy. It is demonstrated that taurin/ dibicor has a positive effect on insulin resistance and body mass in obesity, on carbohydrate and lipid metabolism, on cell membranes, blood pressure, acuity of vision. Taurin/dibicor protects against macro- and microvascular diabetic complications, improves vision, cardiovascular system condition, quality and duration of life.