Interpretation of Key Points in 2024 Chinese Expert Consensus on EGFR Exon 20 Insertion Mutations in Non-Small Cell Lung Cancer

The Chinese Society of Clinical Oncology（CSCO） NSCLC Expert Committee has updated the2023 Chinese expert consensus in light of the growing understanding of epidermal growth factor receptor（EGFR） exon 20 insertion（ex20ins） mutations in non-small cell lung cancer（NSCLC） and the emergence of new clinic...

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Bibliographic Details
Published inZhongliu fangzhi yanjiu Vol. 52; no. 6; pp. 520 - 526
Main Authors Jin, Xuanhong, Zhou, Fei
Format Journal Article
LanguageChinese
English
Published Tianjin China Anti-Cancer Association 2025
Magazine House of Cancer Research on Prevention and Treatment
Subjects
egfr exon 20 insertion
Epidermal growth factor receptors
Growth factors
Insertion
Lung cancer
Mutation
non-small cell lung cancer
Non-small cell lung carcinoma
Small cell lung carcinoma
targeted therapy strategies
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Summary:The Chinese Society of Clinical Oncology（CSCO） NSCLC Expert Committee has updated the2023 Chinese expert consensus in light of the growing understanding of epidermal growth factor receptor（EGFR） exon 20 insertion（ex20ins） mutations in non-small cell lung cancer（NSCLC） and the emergence of new clinical data from targeted therapies. Based on the latest domestic and international literature, clinical evidence, and expert experience, the "Chinese Expert Consensus on the Standardized Diagnosis and Treatment of Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations（2024 Edition）"introduces refinements in the diagnostic and upcoming therapeutic strategies for this rare mutation. This article also highlights the key updates and recommendations in the 2024 consensus compared to the 2023version as well as outlines future directions to optimize clinical practices and improve patient outcomes.
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ISSN:1000-8578
DOI:10.3971/j.issn.1000-8578.2025.25.0120