Short-term Outcomes and Long-term Survival Outcomes of Elderly Patients (Over 80 Years of Age) with Colorectal Cancer Who Received Laparoscopic Versus Open Surgery

• Published in: Zhongliu fangzhi yanjiu Vol. 50; no. 11; pp. 1121 - 1126
• Main Authors: Mao, Zhengqiang, Du, Botao, Sun, Hang, Guo, Dexing, Zhou, Li, Li, Xinyu, Zai, Shoufeng
• Format: Journal Article
• Language: Chinese
• Published: Tianjin China Anti-Cancer Association 01.11.2023; Magazine House of Cancer Research on Prevention and Treatment
• Subjects: Cancer; Colorectal cancer; Colorectal carcinoma; Complications; elderly patients; laparoscopic surgery; Laparoscopy; Matching; Older people; open surgery; Patients; Postoperative; prognosis; Rank tests; Risk factors; short-term outcomes; Surgery; Survival
• ISSN: 1000-8578
• DOI: 10.3971/j.issn.1000-8578.2023.23.0633

Objective To examine short-term outcomes and long-term survival of elderly patients (aged over 80 years) with colorectal cancer who received laparoscopic versus open surgery. Methods A total of 313 patients over 80 years old with colorectal cancer who underwent radical surgery were included. According to the surgical method, all patients were divided into open-surgery group (n=143) and laparoscopic surgery group(n=170). Baseline data were balanced between the two groups by using propensity score matching. Kaplan-Meier was used to draw the survival curve, and survival was compared by Log rank tests. Cox proportional risk model was used to analyze the effects of all factors on overall survival (OS) and disease-free survival (DFS). Results After matching, 93 patients were included in each group. The mean intraoperative blood loss, the incidence of overall postoperative complications and gradeⅠ-Ⅱ complications in the laparoscopic surgery group were significantly lower than those in the open surgery group (all P<0