Correlation between Lymph Node Ratio and Clinicopathological Features and Prognosis of IIIa-N2 Non-small Cell Lung Cancer

IIIa-N2 non-small cell lung cancer was significant different in survival, although N stage of lung cancer based on anatomic location of metastasis lymph node. Lymph node ratio considered of prognostic factor might be the evaluation index for IIIa-N2 non-small cell lung cancer prognosis. Therefore, t...

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Published inZhongguo fei ai za zhi Vol. 22; no. 11; pp. 702 - 708
Main Authors Zhang, Shanyuan, Wang, Liang, Lu, Fangliang, Pei, Yuquan, Yang, Yue
Format Journal Article
LanguageChinese
Published China Chinese Anti-Cancer Association Chinese Antituberculosis Association 20.11.2019
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
Subjects
Biopsy
Carcinoma, Non-Small-Cell Lung - diagnosis
Carcinoma, Non-Small-Cell Lung - pathology
Classification
Female
Humans
iiia-n2
Lung cancer
lung neoplasms
Lung Neoplasms - diagnosis
Lung Neoplasms - pathology
lymph node ratio
Lymphatic Metastasis
Lymphatic system
Male
Medical prognosis
Metastasis
Middle Aged
Multivariate Analysis
Neoplasm Staging
Prognosis
Retrospective Studies
Surgery
Survival Analysis
Thoracic surgery
Beijing China
United States > US
China
IIIa-N2
Prognosis
Lymph node ratio
Lung neoplasms
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Summary:IIIa-N2 non-small cell lung cancer was significant different in survival, although N stage of lung cancer based on anatomic location of metastasis lymph node. Lymph node ratio considered of prognostic factor might be the evaluation index for IIIa-N2 non-small cell lung cancer prognosis. Therefore, the aim of the study was to evaluate the correlation between lymph node ratio and clinicopathological features and prognosis of IIIa-N2 non-small cell lung cancer prognosis. A total of 288 cases of pathological IIIa-N2 non-small cell lung cancer were enrolled who received radical resection at the Department of Thoracic Surgery II, Peking University Cancer Hospital from January 2006 to December 2016. The univariate analysis between clinicopathological variables and lymph node ratio used Pearson's chi-squared test. Cox regression was conducted to identify the independent prognosis factors for IIIa-N2 non-small cell lung cancer. There were 139 cases in the lower lymph node ratio group, another 149 cases in the higher l
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ISSN:1009-3419
1999-6187
DOI:10.3779/j.issn.1009-3419.2019.11.04