Peak Value of Central Venous Pressure and Acute Kidney Injury in Cardiac Patients After Cardiopulmonary Bypass Surgery

• Published in: Xiehe Yixue Zazhi Vol. 13; no. 6; pp. 1005 - 1011
• Main Authors: ZHANG Hongmin, CHEN Xiukai, WANG Xiaoting, LIU Dawei, CHAI Wenzhao
• Format: Journal Article
• Language: Chinese
• Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 01.11.2022
• Subjects: acute kidney injury; cardiac surgery; cardiopulmonary bypass; central venous pressure
• ISSN: 1674-9081
• DOI: 10.12290/xhyxzz.2022-0448

Objective  To explore the relationship between the post-operative peak value of central venous pressure (CVPp) and the incidence of acute kidney injury (AKI) in patients who had undergone cardiopulmonary bypass surgery (CBS).  Methods  Clinical data were retrospectively collected from 1 May 2016 to 1 May 2018 from all patients undergoing CBS in the Department of Intensive Care Medicine, Peking Union Medical College Hospital. The CVP values immediately after transfer to ICU (CVP 0h) and at 6 h(CVP 6h), and CVPp within 48 h(CVPp 48h) of transfer to ICU, the incidence of AKI after 48 h of transfer to ICU and in-hospital mortality were recorded. The receiver operating characteristic (ROC) curve was used to evaluate the clinical value of CVP-related indicators in predicting AKI after CBS and determine the optimal threshold. The risk factors for AKI and in-hospital mortality after CBS were analysed using single factor and multifactorial Logistic regression.  Results  A total of 485 patients after CBS who met the in