Efficacy of autologous platelet-rich plasma intradiscal injection in the treatment of discogenic low back pain

• Published in: Zhongguo lin chuang yan jiu Vol. 37; no. 5; pp. 735 - 738
• Main Author: SHUAI Ming, HE Cheng, ZHAO Lan, SHUANG Feng, JIANG Wenhua, WANG Chao, HU Wenwen, LI Hao
• Format: Journal Article
• Language: Chinese; English
• Published: The Editorial Department of Chinese Journal of Clinical Research 01.05.2024
• Subjects: celecoxib; discogenic low back pain; intradiscal injection; platelet-rich plasma
• ISSN: 1674-8182
• DOI: 10.13429/j.cnki.cjcr.2024.05.017

Objective To investigate the efficacy of intradiscal injection of autologous platelet-rich plasma (PRP) in the treatment of discogenic low back pain (DLBP). b>Methods A retrospective analysis of clinical data from 47 DLBP patients treated at No.908 Hospital of Joint Logistics Support Force from January 2022 to June 2023 was conducted. Patients were divided into a PRP combined with celecoxib capsule treatment group (experimental group, n=16) and a celecoxib capsule monotherapy group (control group, n=31) based on the treatment method. The visual analogue scale (VAS) of low back pain and Oswestry disability index (ODI) scores were recorded before treatment, at 1 week, 1 month, and 6 months after treatment. Results VAS scores and ODI scores in the experimental group gradually decreased over time; the VAS scores and ODI scores in the control group decreased at 1 week after treatment compared to before treatment, but then showed a gradual upward trend. The VAS scores and ODI scores in the experimental group were lower than those in the control group at 1 month and 6 months after treatment (P＜0.05). Conclusion he long-term efficacy of autologous PRP combined with celecoxib capsule in treating DLBP is superior to that of celecoxib capsule monotherapy and can be considered as an effective treatment for DLBP.