Investigation into Parvovirus B19 Antibodies in Serum Samples Sent with Pre-diagnosis of Arthritis-Arthralgia

• Published in: The anatolian journal of family medicine (Online) Vol. 3; no. 1; pp. 40 - 44
• Main Authors: Hilal Türkmen Albayrak, Ayfer Bakır, Mustafa Güney, Mehmet Tevfik Yavuz
• Format: Journal Article
• Language: English
• Published: Turkish Foundation of Family Medicine 01.04.2020
• Subjects: arthralgia; arthritis; enzyme immunoassay; human parvovirus b19
• ISSN: 2651-3455
• DOI: 10.5505/anatoljfm.2019.35220

INTRODUCTION[|]Parvovirus B19 belonging to the Erythrovirus genus is a single-stranded DNA virus in the family Parvoviridae. The present study aims to determine parvovirus B19 seropositivity in serum samples sent with pre-diagnosis of arthritis/arthralgia and to evaluate the age dispersion retrospectively.[¤]METHODS[|]Parvovirus B19 IgM and IgG tests were investigated in serum samples with pre-diagnosis of arthritis/arthralgia sent to Virology Laboratory between January 2017 and February 2019 retrospectively. In serum samples of the patients, parvovirus B19 IgM and IgG tests were investigated using the enzyme immunoassay method.[¤]RESULTS[|]Sixty-one patients with pre-diagnosis of arthritis/arthralgia were included in this study. The mean age of the patients was 45.2+-17.8 years. Parvovirus B19 IgG and IgM positivity rates were 40 (65.6%) and 2 (3.3%), respectively. Parvovirus B19 IgG positivity was highest at the ages over 50 years and lowest at the ages under 30 years (p=0.362). Parvovirus B19 IgG seropositivity was the highest in females with a rate of 72.0% (p=0.241).[¤]DISCUSSION AND CONCLUSION[|]As a result, parvovirus B19 IgG and IgM positivity rates in the patient group with pre-diagnosis of arthritis/arthralgia were 65.6% and 3.3%, respectively, in our study. As the parvovirus B19 seropositivity rate was found high when compared to the general population studies, latent parvovirus B19 infection should be investigated in synovial tissue in patients with chronical arthritis and arthralgia complaints.[¤]