Exploring the Inter- and Intra-Specific Variability of Androctonus Scorpion Venoms
Scorpion venom possesses a lethal sting and potential medicinal properties, making it a captivating natural elixir. Our study aimed to unravel the composition of Androctonus scorpionvenoms in Morocco. Using electrospray mass spectrometry and high-performance liquid chromatography (HPLC), we conducte...
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Published in | Biology and life sciences forum Vol. 24; no. 1; p. 12 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
MDPI AG
01.07.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Scorpion venom possesses a lethal sting and potential medicinal properties, making it a captivating natural elixir. Our study aimed to unravel the composition of Androctonus scorpionvenoms in Morocco. Using electrospray mass spectrometry and high-performance liquid chromatography (HPLC), we conducted a thorough analysis to gain detailed insights into venom composition. The data unveiled a wide range of molecular weights, influenced by factors such as species, genus, location, age, sex, and diet. Short toxins (2000–4000 Da) predominated in the venoms, effectively blocking K+ channels, while larger molecular weights (>4000 Da) corresponded to long toxins that modulate Na+ channels. Furthermore, we made intriguing discoveries of previously unidentified peptides (<2000 Da). This study provides valuable knowledge, shedding light on the intricate composition of scorpion venoms. |
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ISSN: | 2673-9976 |
DOI: | 10.3390/IECT2023-14797 |