Effect of hemodialysis on short-term outcomes after colon cancer surgery

• Published in: PloS one Vol. 17; no. 1; p. e0262531
• Main Authors: Toshio Shiraishi, Tetsuro Tominaga, Takashi Nonaka, Shintaro Hashimoto, Kiyoaki Hamada, Masato Araki, Yorihisa Sumida, Hiroaki Takeshita, Hidetoshi Fukuoka, Hideo Wada, Kazuo To, Mariko Yamashita, Kenji Tanaka, Terumitsu Sawai, Takeshi Nagayasu
• Format: Journal Article
• Language: English
• Published: Public Library of Science (PLoS) 01.01.2022
• ISSN: 1932-6203
• DOI: 10.1371/journal.pone.0262531

BackgroundHemodialysis patients who undergo surgery have a high risk of postoperative complications. The aim of this study was to determine whether colon cancer surgery can be safely performed in hemodialysis patients.MethodsThis multicenter retrospective study included 1372 patients who underwent elective curative resection surgery for colon cancer between April 2016 and March 2020.ResultsOf the total patients, 19 (1.4%) underwent hemodialysis, of whom 19 (100%) had poor performance status and 18 had comorbidities (94.7%). Minimally invasive surgery was performed in 78.9% of hemodialysis patients. The postoperative complication rate was significantly higher in hemodialysis than non-hemodialysis patients (36.8% vs. 15.5%, p = 0.009). All postoperative complications in the hemodialysis patients were infectious type. Multivariate analysis revealed a significant association of hemodialysis with complications (odds ratio, 2.9362; 95%CI, 1.1384-7.5730; p = 0.026).ConclusionDespite recent advances in perioperative management and minimally invasive surgery, it is necessary to be aware that short-term complications can still occur, especially infectious complications in hemodialysis patients.