Molecular and pathomorphological prognostic markers for melanoma: Current approaches and prospects

The incidence of melanoma demonstrates a persistent increasing tendency, which justifies the need to study and identify new prognostic markers for the development and course of this disease. The given paper shows current approaches to melanoma staging, including those to applying pathomorphological...

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Bibliographic Details
Published inArkhiv patologii Vol. 77; no. 4; p. 71
Main Authors Ruksha, T G, Aksenenko, M B, Shvetsova, Yu I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.2015
Subjects
Biomarkers, Tumor
Cyclin-Dependent Kinase Inhibitor p16 - genetics
Epigenesis, Genetic
Genetic Markers
Humans
Melanoma - genetics
Melanoma - metabolism
Melanoma - pathology
MicroRNAs - genetics
Neoplasm Staging
Prognosis
Skin Neoplasms - genetics
Skin Neoplasms - metabolism
Skin Neoplasms - pathology
Tumor Microenvironment
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Summary:The incidence of melanoma demonstrates a persistent increasing tendency, which justifies the need to study and identify new prognostic markers for the development and course of this disease. The given paper shows current approaches to melanoma staging, including those to applying pathomorphological prognostic criteria, and discusses prospects for using the results of genomic and epigenomic studies of the carcinoma in clinical practice.
ISSN:0004-1955
DOI:10.17116/patol201577471-77