Preinvasive lesions in gynaecology - uterine cervix

• Published in: Klinická onkologie Vol. 26 Suppl; p. S49
• Main Authors: Mouková, L, Feranec, R, Chovanec, J
• Format: Journal Article
• Language: Czech; English
• Published: Czech Republic 15.12.2013
• Subjects: Cell Transformation, Neoplastic; Cervical Intraepithelial Neoplasia - diagnosis; Cervical Intraepithelial Neoplasia - pathology; Cervical Intraepithelial Neoplasia - therapy; Female; Humans; Mass Screening; Papillomavirus Infections - diagnosis; Papillomavirus Infections - pathology; Papillomavirus Infections - therapy; Papillomavirus Vaccines - administration & dosage; Precancerous Conditions; Risk Factors; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - therapy; preinvasive lesions - uterine cervix - cervical intraepithelial neoplasia - human papillomavirus - vaccination
• ISSN: 0862-495X
• DOI: 10.14735/amko2013S49

Preinvasive lesion of the uterine cervix can give rise to cervical cancer. High-risk human papillomaviruses with high oncogenic potential are considered to be the main etiopathological factors with interaction of other risk factors (recurrent inflammation of the cervix, injury of the cervix, immunosuppressive conditions, sexual promiscuity, etc.). Early dia-gnosis of these changes at regular gynecological examinations and adequate treatment can prevent of malignant transformation. Organized cervical screening and implementation of nationwide vaccination against human papillomavirus promises to reduce the incidence of cervical cancer.