Serious Necrotizing Enterocolitis in a Neonate Treated with Octreotide for Congenital Chylothorax

The somatostatin analog octreotide has recently been introduced in the treatment of infants with chylothorax. The safety profile of octreotide has not been fully evaluated. Octreotide reduces the splanchnic blood flow in a dose-dependent manner, affecting the entire gastrointestinal tract. Some conc...

Full description

Saved in:
Bibliographic Details
Published inPERINATOLOGY (구 대한주산의학회잡지) Vol. 30; no. 4; pp. 249 - 253
Main Authors Jo, Min Jeong, Kim, Do-Hyun, Kim, Hee Sup
Format Journal Article
LanguageKorean
Published 대한주산의학회 31.12.2019
Subjects
Chylothorax
Enterocolitis
necrotizing
Newborn
Octreotide
의학일반
Online AccessGet full text

Cover

More Information
Summary:The somatostatin analog octreotide has recently been introduced in the treatment of infants with chylothorax. The safety profile of octreotide has not been fully evaluated. Octreotide reduces the splanchnic blood flow in a dose-dependent manner, affecting the entire gastrointestinal tract. Some concern has been recently raised regarding the potential implications of this effect in the development of necrotizing enterocolitis in neonates receiving octreotide for congenital hyperinsulinism or chylothorax. To our knowledge, there is no case report linking the use of octreotide with necrotizing enterocolitis in Korea. We report a case of serious necrotizing enterocolitis in a neonate treated with octreotide for congenital idiopathic chylothorax.
ISSN:2508-4887
2508-4895
DOI:10.14734/PN.2019.30.4.249