RARE CASE OF LANGERHANS CELL HISTIOCYTOSIS IN AN ELDERLY PATIENT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 134; no. 3; p. e112
• Main Authors: Gomes, Bruna Yasmin, De Oliveira, Letycia Maria Lopes, De Oliveira, Leandro Cancellara, Da Silva, Marcio Roberto Barbosa, Mendonça, Elismauro Francisco, Silva, Geisa Badauy Lauria, Lima, Bruno Miranda Silva
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.09.2022
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2022.01.173

Langerhans cell histiocytosis (LCH) is a disease in which there is proliferation of dendritic mononuclear cells with local or diffuse infiltration of the organs. Most cases occur in children. Oral manifestations are common and include mucosal ulcerations, bone involvement, periodontal disease, and granulomas. The diagnosis is based mainly on histologic analysis. A 75-year-old male patient reported for consultation with the main complaint of mouth sores that do not heal. Clinical examination revealed ulcerated lesions on the hard palate and alveolar ridge of the posterior teeth and the presence of teeth with bone loss and mobility. Incisional biopsy was performed and the anatomopathologic examination confirmed the diagnosis of LCH. Complementary exams were requested for staging and therapeutic definition. Therefore, it is necessary for the dental surgeon to know the characteristics of this disease and include them in the differential diagnosis of lesions that affect the oral cavity.