DIFFUSE LARGE B-CELL LYMPHOMA IN THE BUCCAL MUCOSA - A CASE REPORT

A 67-year-old female patient presented a complaint of an asymptomatic oral lump, lasting about 10 years, which had recently shown an expressive growth. The patient reported a salpingectomy 40 years before; absence of any current medication, and no history of smoking or alcohol intake. Clinical exami...

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Published inOral surgery, oral medicine, oral pathology and oral radiology Vol. 136; no. 1; p. e63
Main Authors WEGNER, Everton Adriano, FIGUEIREDO, Maria Antonia, SALUM, Fernanda Gonçalves, KOTH, Valesca Sander, CHERUBINI, Karen
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.07.2023
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Summary:A 67-year-old female patient presented a complaint of an asymptomatic oral lump, lasting about 10 years, which had recently shown an expressive growth. The patient reported a salpingectomy 40 years before; absence of any current medication, and no history of smoking or alcohol intake. Clinical examination showed two submucous mobile nodules, firm to palpation, one in the right buccal mucosa, measuring 1.5 cm X 1.2 cm, and the other on the left side of the floor of the mouth with 0.7 cm X 0.8 cm. Lymphadenopathy was observed in the right submandibular region. Laboratory tests showed anemia, leukocytosis, and an erythrocyte sedimentation rate of 89 mm/h. Other tests, including anti-HCV and anti-HIV, were normal. Excisional biopsy of the buccal mucosa nodule was performed, and hematoxylin/eosin and immunohistochemical analyses revealed the diagnosis of diffuse large B-cell lymphoma. The patient was referred to oncology services and started chemotherapy.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2023.03.211