CLINICAL AND MORPHOLOGIC PROFILE OF ORAL TONGUE SQUAMOUS CELL CARCINOMA: A RETROSPECTIVE STUDY

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 129; no. 1; p. e151
• Main Authors: MOSCONI, CARLA, GONÇALVES, JULIE ANE MARIA, SILVA, RICARDO NATÃ FONSECA, ALVES, POLLIANNA MUNIZ, DO LAGO COSTA, NÁDIA, DE MENDONÇA, ELISMAURO FRANCISCO, BATISTA, ALINE CARVALHO
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.01.2020
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2019.06.650

Oral tongue squamous cell carcinoma (OTSCC) is a malignant neoplasm that is quite aggressive with a poor prognosis. Therefore, this study described clinicopathologic characteristics of a series of cases of OTSCC. Observational and cross-sectional research. Sample consisted of 76 cases of OTSCC diagnosed in an oncology referral hospital, within a 16-year period (2000 to 2016). Clinical characteristics of patients (age, sex, and tobacco or alcohol habits, treatment, and survival) and lesions (tumor size, locoregional metastasis, distant metastasis, clinical stage, and recurrence) were obtained from medical records. Morphologic analysis was based on the World Health Organization (2017). Statistical analysis was descriptive. Mean age of patients was 57.24 years. OTSCC was more frequent in males (n = 53; 69.73%), associated with tobacco or alcohol habits (n = 54; 71.05%), and tumor size T3/T4 (n = 42; 55.26%). The most recommended treatment was surgery associated radiotherapy and chemotherapy (n = 37; 48.68%). Local and distant metastasis occurred in 56.57% (n = 43) and 10.52% (n = 8), respectively. Advanced clinical stages III/IV (n = 54; 71.05%) were predominant. OTSCC without recurrence was higher (n = 61; 80.26%). Overall survival was ± 51.47 months. The results showed that OTSCC is more common in smokers and drinkers of the male sex, and the latter diagnosis can be responsible for lower survival of these patients.