Focus on RNA sequencing quality control (SEQC)

Over 70% of the human genome can be transcribed, yet never all in the same cell type, according to recent ENCODE project results, and a wealth of long, small, micro and even circular RNAs have been found in nature. To study this remarkable diversity of transcripts researchers have developed many tec...

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Bibliographic Details
Published inNature biotechnology Vol. 32; no. 9; p. vii
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group 09.09.2014
Subjects
Cells
Human Genome Project
Quality control
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Summary:Over 70% of the human genome can be transcribed, yet never all in the same cell type, according to recent ENCODE project results, and a wealth of long, small, micro and even circular RNAs have been found in nature. To study this remarkable diversity of transcripts researchers have developed many techniques,but none is as comprehensive and powerful as high-throughput sequencing of RNA (RNA-seq). This technology, particularly its use in large-scale collaborative studies, is the subject of this Focus on RNA sequencing quality control (SEQ
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ISSN:1087-0156
1546-1696
DOI:10.1038/nbt.3025