Study on quality standard of Berberidis Cortex

In order to establish the quality standard of Berberidis Cortex and improve its quality control level, water, total ash, acid-insoluble ash and alcohol-soluble extract were determined according to procedures recorded in the Chinese Pharmacopoeia (2010 edition). The qualitative and quantitative analy...

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Bibliographic Details
Published inZhongguo zhongyao zazhi Vol. 41; no. 4; p. 592
Main Authors Li, Yan, Lv, Xiu-Mei, Lin, Ya-Li, Mo, Jia-Qi, Fan, Gang, Lai, Xian-Rong, Zhang, Yi
Format Journal Article
LanguageChinese
English
Published China 01.02.2016
Subjects
Berberine Alkaloids - analysis
Berberis - chemistry
Chromatography, High Pressure Liquid - methods
Chromatography, Thin Layer - methods
Drugs, Chinese Herbal - analysis
Drugs, Chinese Herbal - standards
Quality Control
Berberidis Cortex
magnoflorine
palmatine
jatrorrhizine
quality standard
berberine
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Summary:In order to establish the quality standard of Berberidis Cortex and improve its quality control level, water, total ash, acid-insoluble ash and alcohol-soluble extract were determined according to procedures recorded in the Chinese Pharmacopoeia (2010 edition). The qualitative and quantitative analyses were performed by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC) methods. The results showed that TLC identification had a good resolution with clear spots. The water content was 8.39%-12.23%; total ash was 4.50%-9.96%; acid-insoluble ash was 0.10%-0.69%, and the alcohol-soluble extraction was 20.62%-37.13%. The average contents of magnoflorine, jatrorrhizine, palmatine, and berberine in Berberidis Cortex were 5.98%, 0.63%, 0.30%, 2.50%, respectively. It was concluded that the developed method was accurate and good in specificity, which can be used for quality control of Berberidis Cortex in the future.
ISSN:1001-5302
DOI:10.4268/cjcmm20160407