Dyslipidemia in patients hospitalized for stroke at the Clinic of Neuroscience Ibrahima Pierre Ndiaye, Fann National Teaching Hospital in Dakar – Senegal

• Published in: Journal of the neurological sciences Vol. 405; p. 2
• Main Authors: Mansare, M.L., Kamadore, T., Maouly, F., Gallo, D. Amadou
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.10.2019
• Subjects: Dyslipidemia; Senegal; Stroke; Senegal; Stroke; Dyslipidemia
• ISSN: 0022-510X; 1878-5883
• DOI: 10.1016/j.jns.2019.10.414

The objective of our study was to study the lipid profile of patients hospitalized for stroke (Ischemic or Hemorrhagic) by identifying among them, those who presented dyslipidemias. We conducted a study on the lipidogram results of 609 patients hospitalized for stroke. All the variables were included in the model a priori without any selection, with, first, the lipid variables, then secondarily the age, the sex. The stroke rate was 72% for the ischemic form and 28% for the hemorrhagic form. It had increased with age regardless of the ischemic or hemorrhagic type. The extreme ages were 17 and 95 years old with an average of 62.8 years. Men accounted for 53% of cases and women 47% of cases. The averages and standard deviations of the lipid fractions analyzed were respectively: TC (1.89, 0.55); HDL (0.49, 0.24); LDL (1.24, 0.50) and TG (0.90, 0.41). After controlling for confounders by bivariate analysis, the result for pure dyslipidemia showed that HDL was significantly associated with stroke in the foreground [OR 1.77; 95% CI 1.15-2.72; p = 0.002] followed by LDL [OR 2.00; 95% CI 1.04-4.87; p = 0.03]. No significant association could be found between TG, TC and stroke. The overall mortality rate was 25% (154 cases). In this study, the occurrence of fatal stroke was associated with significant lowering of HDL cholesterol. From our point of view, it is important to study this type of lipid profile well.