A Brief Review of Vehicles for Topical Therapies

Topical therapy has been a fundamental part of dermatology, evolving from early ointments to advanced transdermal treatments. These formulations allow for effective management of skin conditions by maximizing local drug delivery and minimizing systemic effects. Modern topical therapies continue to b...

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Bibliographic Details
Published inSkin pharmacology and physiology p. 1
Main Authors Ahuja, Kripa, An, Miranda, Lio, Peter
Format Journal Article
LanguageEnglish
Published Switzerland 12.09.2024
Subjects
Drug delivery
Pharmacology
Emulsion
Topical agents
Diffusion
Vehicles
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Summary:Topical therapy has been a fundamental part of dermatology, evolving from early ointments to advanced transdermal treatments. These formulations allow for effective management of skin conditions by maximizing local drug delivery and minimizing systemic effects. Modern topical therapies continue to benefit from innovations that improve both efficacy and patient outcomes. Topical formulations consist of a vehicle and active ingredients, with the vehicle enhancing drug absorption and patient experience. Historically categorized by physical properties, vehicles are vital in drug delivery. Recent innovations, such as nanoemulsions and derma-membrane structures, offer improved skin penetration and therapeutic results, representing significant advancements in topical treatment options. Topical therapies provide targeted, effective treatment in dermatology with minimal systemic side effects. Vehicle choice is essential to therapy success, and innovations such as nanoemulsions are improving drug delivery and patient care. Ongoing research into novel delivery systems continues to enhance the future of dermatological treatments.
ISSN:1660-5535
DOI:10.1159/000541418