Oral desensitization with Ketocal® in an infant with ketogenic diet and cow's milk protein allergy

• Published in: Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral Vol. 39; no. 6; pp. 1427 - 1431
• Main Authors: Benítez Provedo, Cristina, Martínez Ibeas, María Angeles, Losada Del Pozo, Rebeca, Montes Arjona, Ana María, Blanco Rodríguez, Miriam, Del Río Camacho, Genoveva
• Format: Journal Article
• Language: Spanish; English
• Published: Spain 20.12.2022
• Subjects: Animals; Cattle; Diet, Ketogenic; Female; Male; Milk Hypersensitivity - therapy; Milk Proteins; Dieta cetogénica. Alergia a proteínas de leche de vaca. Inmunoterapia oral
• ISSN: 0212-1611; 1699-5198
• DOI: 10.20960/nh.04003

Introduction: ketogenic diet is a treatment with proven efficacy in drug-refractory childhood epilepsy. Cow's milk protein allergy may be a limitation for treating infants with ketogenic diet, as they need a product that contains cow's milk protein (Ketocal®). Case report: we report the case of an infant with a drug-refractory epileptic encephalopathy and IgE-mediated cow's milk protein allergy, who started a classic ketogenic diet. Oral desensitization was achieved with Ketocal 3:1®, allowing its use in the diet and achieving a clinical improvement with seizure control. Discussion: a patient with epilepsy and cow's milk protein allergy can benefit from the ketogenic diet, since it is possible to perform an oral immunotherapy with Ketocal®, also achieving a probable resolution of his/her allergy.