Anaplastic Large Cell Lymphoma CD30+ ALK- in the Oral Cavity as a Primary Manifestation in HIV+ Patient Case Report

Anaplastic large cell lymphoma (ALCL) is a rare subtype of T-cell lymphoma that may involve mucocutaneous sites, in primary form, or secondary to systemic disease. It is a systemic malignancy characterized by an extranodal phenotype that rarely occurs in the oral cavity as the first manifestation of...

Full description

Saved in:
Bibliographic Details
Published inJournal of Oral Diagnosis Vol. 4; pp. 1 - 5
Main Authors Leonardi, Nicolás, Caciva, Ricardo Christían, Piemonte, Eduardo David, Brusa, Martín, Sambuelli, Rubén, Allende, Adrián, Panico, René Luis
Format Journal Article
LanguagePortuguese
Published 15.01.2019
Online AccessGet full text

Cover

More Information
Summary:Anaplastic large cell lymphoma (ALCL) is a rare subtype of T-cell lymphoma that may involve mucocutaneous sites, in primary form, or secondary to systemic disease. It is a systemic malignancy characterized by an extranodal phenotype that rarely occurs in the oral cavity as the first manifestation of acquired immunodeficiency syndrome. In the primary forms, ALCL stands out for its favorable prognosis, being important to differentiate them clinically from the secondary ones, which have a rapid and aggressive evolution. For its diagnosis, it requires a rigorous physical and clinical examination and a duly oriented anatomopathological and immunohistochemical evaluation. In the present work, a clinical case of ALCL secondary to HIV is presented, detailing clinical characteristics, anatomopathological description, immunohistochemical profile and evolution against treatment.
ISSN:2525-5711
2525-5711
DOI:10.5935/2525-5711.20190010