Ocular side effects in tuberculosis patients receiving direct observed therapy containing ethambutol

The detailed history, best-corrected visual acuity (BCVA), color vision, fundus examination, visual field, retinal nerve fiber layer (RNFL) thickness, and central subfield macular thickness were carried out in all patients pretreatment and then at the 2nd month of treatment. [12] Visual acuity, cont...

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Published inNational journal of physiology, pharmacy and pharmacology Vol. 12; no. 2; pp. 1 - 131
Main Authors Dave, Aarti, Shah, Surohi, Mistry, Yogin, Chaturvedi, Naina, Jariwala, Disha
Format Journal Article
LanguageEnglish
Published Surat Association of Physiologists, Pharmacists & Pharmacologists 01.01.2022
Subjects
Color blindness
Diabetic retinopathy
Drug dosages
Ophthalmology
Optics
Patients
Tomography
Tuberculosis
India
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Summary:The detailed history, best-corrected visual acuity (BCVA), color vision, fundus examination, visual field, retinal nerve fiber layer (RNFL) thickness, and central subfield macular thickness were carried out in all patients pretreatment and then at the 2nd month of treatment. [12] Visual acuity, contrast sensitivity, color vision, and pattern reversal visual evoked potential are some sensitive tests recommended to detect drug induced ocular toxicity in subclinical stages, but still reversibility of toxicity depends on early diagnosis and early cessation of the culprit drug. [...]other visual parameters such as central subfield macular thickness and peri-papillary RNFL thickness as measured by SD-optical coherence tomography may prove to be an important tool for early detection. Patients on drugs causing color vision deficiency such as indomethacin, OC pills and digoxin, and known cases of color blindness were also excluded from the study.
ISSN:2320-4672
2231-3206
DOI:10.5455/njppp.2022.12.08272202113082021