Electrocatalytic Oxidation of Cysteine at a CoSalophen/ n ‐(butyl) 4 SiW 12 O 40 Carbon Paste Electrode
Abstract In the present study, a novel mixture consisting of N , N ′‐bis(salicylidene)‐1,2‐phenylenediamino cobalt (CoSalophen, CoSal) complex and ( n ‐butyl) 4 SiW 12 O 40 (SiW 12 ), have been used to chemically modify a carbon paste electrode (CPE) for sensitive determination of cysteine (CySH). T...
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| Published in | Electroanalysis (New York, N.Y.) Vol. 25; no. 9; pp. 2100 - 2108 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
01.09.2013
|
| Online Access | Get full text |
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| Summary: | Abstract
In the present study, a novel mixture consisting of
N
,
N
′‐bis(salicylidene)‐1,2‐phenylenediamino cobalt (CoSalophen, CoSal) complex and (
n
‐butyl)
4
SiW
12
O
40
(SiW
12
), have been used to chemically modify a carbon paste electrode (CPE) for sensitive determination of cysteine (CySH). The electrocatalytic effect of the newly developed modified CPE towards oxidation of CySH was evaluated by comparing cyclic and differential pulse voltammograms in the presence of cysteine at bare, CoSal, SiW
12
and CoSal/SiW
12
modified CPE. The differential pulse voltammetry method was applied as a sensitive method for quantitative detection of CySH trace amounts, the experimental conditions being optimized in order to evaluate the best analytical parameters of the sensor. Reproducibility and stability studies were also performed and the sensor was applied for the determination of CySH in a pharmaceutical sample and in human blood serum and urine samples. |
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| ISSN: | 1040-0397 1521-4109 |
| DOI: | 10.1002/elan.201300235 |