Supercritical CO 2 Extraction of Carotenoids (Astaxanthin, Adonirubin, and Adonixanthin) from Paracoccus carotinifaciens : Improved Z ‐Isomer Ratio and Recovery of Carotenoids via High‐Temperature Extraction
Abstract The effects of high‐temperature supercritical CO 2 (SC‐CO 2 ) extraction on Z ‐isomerization and recovery of carotenoids (astaxanthin, adonirubin, and adonixanthin) from Paracoccus carotinifaciens are investigated. The high‐temperature extraction, especially at >100 °C, not only increase...
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| Published in | European journal of lipid science and technology Vol. 124; no. 7 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
01.07.2022
|
| Online Access | Get full text |
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| Abstract | Abstract
The effects of high‐temperature supercritical CO
2
(SC‐CO
2
) extraction on
Z
‐isomerization and recovery of carotenoids (astaxanthin, adonirubin, and adonixanthin) from
Paracoccus carotinifaciens
are investigated. The high‐temperature extraction, especially at >100 °C, not only increases the total
Z
‐isomer ratio of carotenoids in the resulting extracts but also improves carotenoid recovery. For example, when the SC‐CO
2
extraction is performed at 60 °C and 30 MPa with an entrainer (ethanol), the total
Z
‐isomer ratio and the recovery of astaxanthin are 11.1% and 28.4%, respectively, whereas at 120 °C, the values increase to 54.2 and 56.4%, respectively. The significant improvement in the extraction efficiency of carotenoids at high temperatures can be attributed to the increase in the ratio of carotenoid
Z
‐isomers with high solubility in SC‐CO
2
. Moreover, the effects of extraction pressure and entrainer content on
Z
‐isomerization and recovery of carotenoids are also investigated. The results show that higher pressure and ethanol content resulted in lower
Z
‐isomer ratios and higher recoveries of carotenoids. As the
Z
‐isomers of carotenoids have greater bioavailability and potentially exhibit superior biological activities than the all‐
E
‐isomers, high value‐added carotenoids, and higher yield can be simultaneously achieved with high‐temperature extraction.
Practical applications
: As carotenoid extraction is usually performed using toxic organic solvents, residual solvents are a serious concern. In addition, naturally occurring carotenoids (mainly the all‐
E
‐isomers) have low bioavailability. These are important issues that need to be overcome for the industrial use of carotenoids. The
Z
‐isomer‐rich carotenoids obtained by SC‐CO
2
extraction under high‐temperature conditions have great potential to solve these issues simultaneously. |
|---|---|
| AbstractList | Abstract
The effects of high‐temperature supercritical CO
2
(SC‐CO
2
) extraction on
Z
‐isomerization and recovery of carotenoids (astaxanthin, adonirubin, and adonixanthin) from
Paracoccus carotinifaciens
are investigated. The high‐temperature extraction, especially at >100 °C, not only increases the total
Z
‐isomer ratio of carotenoids in the resulting extracts but also improves carotenoid recovery. For example, when the SC‐CO
2
extraction is performed at 60 °C and 30 MPa with an entrainer (ethanol), the total
Z
‐isomer ratio and the recovery of astaxanthin are 11.1% and 28.4%, respectively, whereas at 120 °C, the values increase to 54.2 and 56.4%, respectively. The significant improvement in the extraction efficiency of carotenoids at high temperatures can be attributed to the increase in the ratio of carotenoid
Z
‐isomers with high solubility in SC‐CO
2
. Moreover, the effects of extraction pressure and entrainer content on
Z
‐isomerization and recovery of carotenoids are also investigated. The results show that higher pressure and ethanol content resulted in lower
Z
‐isomer ratios and higher recoveries of carotenoids. As the
Z
‐isomers of carotenoids have greater bioavailability and potentially exhibit superior biological activities than the all‐
E
‐isomers, high value‐added carotenoids, and higher yield can be simultaneously achieved with high‐temperature extraction.
Practical applications
: As carotenoid extraction is usually performed using toxic organic solvents, residual solvents are a serious concern. In addition, naturally occurring carotenoids (mainly the all‐
E
‐isomers) have low bioavailability. These are important issues that need to be overcome for the industrial use of carotenoids. The
Z
‐isomer‐rich carotenoids obtained by SC‐CO
2
extraction under high‐temperature conditions have great potential to solve these issues simultaneously. |
| Author | Murakami, Kazuya Hirasawa, Kazuaki Honda, Masaki Osawa, Yukiko Kuroda, Ikuo Kawashima, Yuki Wasai, Masafumi |
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| CitedBy_id | crossref_primary_10_1016_j_fbio_2024_104645 crossref_primary_10_1016_j_biortech_2022_128499 crossref_primary_10_1016_j_molstruc_2023_135958 |
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| References | e_1_2_9_30_1 e_1_2_9_31_1 e_1_2_9_11_1 e_1_2_9_10_1 e_1_2_9_35_1 e_1_2_9_13_1 e_1_2_9_32_1 e_1_2_9_12_1 e_1_2_9_33_1 e_1_2_9_15_1 e_1_2_9_38_1 e_1_2_9_14_1 e_1_2_9_39_1 e_1_2_9_17_1 e_1_2_9_36_1 e_1_2_9_16_1 e_1_2_9_37_1 e_1_2_9_19_1 Honda M. (e_1_2_9_21_1) 2021 e_1_2_9_18_1 e_1_2_9_41_1 e_1_2_9_42_1 e_1_2_9_20_1 e_1_2_9_40_1 e_1_2_9_22_1 e_1_2_9_24_1 e_1_2_9_23_1 e_1_2_9_8_1 e_1_2_9_7_1 e_1_2_9_6_1 e_1_2_9_5_1 e_1_2_9_4_1 e_1_2_9_3_1 Cvjetko M. (e_1_2_9_34_1) 2012; 50 e_1_2_9_2_1 Hayashi M. (e_1_2_9_1_1) 2021 e_1_2_9_9_1 e_1_2_9_26_1 e_1_2_9_25_1 e_1_2_9_28_1 e_1_2_9_27_1 e_1_2_9_29_1 |
| References_xml | – ident: e_1_2_9_20_1 doi: 10.1021/acs.jafc.7b04254 – ident: e_1_2_9_38_1 doi: 10.1002/ejlt.201800191 – ident: e_1_2_9_16_1 doi: 10.1016/j.foodchem.2021.130119 – ident: e_1_2_9_13_1 doi: 10.1021/ie051357k – ident: e_1_2_9_3_1 doi: 10.1351/pac199163010141 – ident: e_1_2_9_15_1 doi: 10.1016/j.biortech.2007.10.049 – ident: e_1_2_9_29_1 doi: 10.1002/ejlt.201900462 – ident: e_1_2_9_5_1 doi: 10.5650/jos.62.181 – ident: e_1_2_9_7_1 doi: 10.3390/nu10040522 – ident: e_1_2_9_27_1 doi: 10.1002/jrs.4459 – ident: e_1_2_9_37_1 doi: 10.1016/j.rser.2017.06.064 – ident: e_1_2_9_9_1 doi: 10.1021/jf8026292 – ident: e_1_2_9_12_1 doi: 10.1155/2016/3164312 – ident: e_1_2_9_10_1 doi: 10.1039/c3ay26295b – ident: e_1_2_9_35_1 doi: 10.1016/j.supflu.2018.01.002 – volume-title: Carotenoids: Biosynthetic and Biofunctional Approaches year: 2021 ident: e_1_2_9_1_1 contributor: fullname: Hayashi M. – ident: e_1_2_9_14_1 doi: 10.1016/j.supflu.2014.05.013 – ident: e_1_2_9_32_1 doi: 10.1021/jp8019705 – ident: e_1_2_9_33_1 doi: 10.1016/j.fbp.2012.03.003 – ident: e_1_2_9_23_1 doi: 10.1016/j.lwt.2017.07.046 – ident: e_1_2_9_36_1 doi: 10.1007/s11746-007-1158-x – ident: e_1_2_9_8_1 doi: 10.1016/j.foodchem.2017.07.099 – ident: e_1_2_9_31_1 doi: 10.1080/09168451.2016.1249454 – ident: e_1_2_9_41_1 doi: 10.1016/j.supflu.2021.105383 – volume-title: Studies in Natural Products Chemistry year: 2021 ident: e_1_2_9_21_1 contributor: fullname: Honda M. – volume: 50 start-page: 208 year: 2012 ident: e_1_2_9_34_1 publication-title: Food Technol. Biotechnol. contributor: fullname: Cvjetko M. – ident: e_1_2_9_4_1 doi: 10.1021/jf991106k – ident: e_1_2_9_28_1 doi: 10.1016/j.ejbt.2018.05.002 – ident: e_1_2_9_30_1 doi: 10.1021/acs.iecr.1c02101 – ident: e_1_2_9_24_1 doi: 10.15261/serdj.25.47 – ident: e_1_2_9_26_1 doi: 10.1021/acsfoodscitech.1c00231 – ident: e_1_2_9_19_1 doi: 10.1021/acs.jafc.9b02102 – ident: e_1_2_9_11_1 doi: 10.1016/j.tifs.2020.07.016 – ident: e_1_2_9_17_1 doi: 10.1021/acs.jafc.1c00087 – ident: e_1_2_9_39_1 doi: 10.1002/bit.10357 – ident: e_1_2_9_40_1 doi: 10.1002/elsc.201100157 – ident: e_1_2_9_6_1 doi: 10.1016/j.phrs.2018.08.012 – ident: e_1_2_9_18_1 doi: 10.1111/asj.13512 – ident: e_1_2_9_42_1 doi: 10.1016/j.foodchem.2005.05.032 – ident: e_1_2_9_22_1 doi: 10.3390/molecules24112149 – ident: e_1_2_9_2_1 doi: 10.3390/sym12060923 – ident: e_1_2_9_25_1 doi: 10.1016/j.procbio.2019.10.005 |
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| Snippet | Abstract
The effects of high‐temperature supercritical CO
2
(SC‐CO
2
) extraction on
Z
‐isomerization and recovery of carotenoids (astaxanthin, adonirubin, and... |
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| Title | Supercritical CO 2 Extraction of Carotenoids (Astaxanthin, Adonirubin, and Adonixanthin) from Paracoccus carotinifaciens : Improved Z ‐Isomer Ratio and Recovery of Carotenoids via High‐Temperature Extraction |
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