Highly Selective In Vivo Imaging of Endogenous/Exogenous Phosphate Ion over ATP and PP i

Abstract A chemodosimeter was designed to function as a highly selective phosphate ion (P i ) sensor, showing a 91‐fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase‐catalyzed P i generation and was the first probe able to trace the generati...

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Published inChemistry, an Asian journal Vol. 10; no. 5; pp. 1165 - 1169
Main Authors Zhang, Jun Feng, Guo, Lin E, Zang, Tie Nan, Duan, Yu Lian, Liu, Xin Yi, Yang, Zhigang, Verwilst, Peter, Luo, Kaijun, Wang, Guang Ke, Kou, Jun Feng, Zhou, Ying, Kim, Jong Seung
Format Journal Article
LanguageEnglish
Published 01.05.2015
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Summary:Abstract A chemodosimeter was designed to function as a highly selective phosphate ion (P i ) sensor, showing a 91‐fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase‐catalyzed P i generation and was the first probe able to trace the generation and enrichment of P i through hemichannel closure in Sf9 cells.
ISSN:1861-4728
1861-471X
DOI:10.1002/asia.201500091