Chronic pain patients can be classified into four groups: Clustering-based discriminant analysis of psychometric data from 4665 patients referred to a multidisciplinary pain centre (a SQRP study)

• Published in: PloS one Vol. 13; no. 2; p. e0192623
• Main Authors: Bäckryd, Emmanuel, Persson, Elisabeth B., Larsson, Annelie Inghilesi, Fischer, Marcelo Rivano, Gerdle, Björn
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.02.2018; Public Library of Science (PLoS)
• Subjects: Annan hälsovetenskap; Biology and Life Sciences; Care and treatment; Chronic pain; Chronic Pain - classification; Chronic Pain - psychology; Cluster Analysis; Diagnosis; Discriminant Analysis; Female; Health Sciences; Humans; Hälsovetenskap; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Medicine and Health Sciences; Other Health Sciences; Pain Management - methods; Patient Satisfaction; Physical Sciences; Psychometrics; Research and Analysis Methods; Social Sciences; Sweden; Sweden
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0192623

To subgroup chronic pain patients using psychometric data and regress the variables most responsible for subgroup discrimination. Cross-sectional, registry-based study. Chronic pain patients assessed at a multidisciplinary pain centre between 2008 and 2015. Data from the Swedish quality registry for pain rehabilitation (SQRP) were retrieved and analysed by principal component analysis, hierarchical clustering analysis, and partial least squares-discriminant analysis. Four subgroups were identified. Group 1 was characterized by low "psychological strain", the best relative situation concerning pain characteristics (intensity and spreading), the lowest frequency of fibromyalgia, as well as by a slightly older age. Group 2 was characterized by high "psychological strain" and by the most negative situation with respect to pain characteristics (intensity and spreading). Group 3 was characterized by high "social distress", the longest pain durations, and a statistically higher frequency of females. The frequency of three neuropathic pain conditions was generally lower in this group. Group 4 was characterized by high psychological strain, low "social distress", and high pain intensity. The identification of these four clusters of chronic pain patients could be useful for the development of personalized rehabilitation programs. For example, the identification of a subgroup characterized mainly by high perceived "social distress" raises the question of how to best design interventions for such patients. Differentiating between clinically important subgroups and comparing how these subgroups respond to interventions is arguably an important area for further research.