MORPHOFUNCTIONAL CHARACTERISTICS TESTES WISTAR RATS EXPOSED TO LPS IN GIPERANDROGENEMII

We investigated the morphological changes of the testes of Wistar rats with acute gram-negative ENDOTOXICOSIS against giperandrogenemii. In acute ENDOTOXICOSIS 1 st day after injection of lipopolysaccharide (LPS) showed a reduction in the level of total testosterone in serum, increase of Leydig cell...

Full description

Saved in:
Bibliographic Details
Published inI.P. Pavlov Russian Medical Biological Herald Vol. 19; no. 2; p. 5
Main Authors Vasil'eva, Svetlana Gennad'evna, Mkhitarov, V A, Kosyreva, A M, Makarova, O V, Vassilievа, S G, Kosyrevа, A M, Makarovа, O V
Format Journal Article
LanguageEnglish
Published 15.06.2011
Online AccessGet full text

Cover

More Information
Summary:We investigated the morphological changes of the testes of Wistar rats with acute gram-negative ENDOTOXICOSIS against giperandrogenemii. In acute ENDOTOXICOSIS 1 st day after injection of lipopolysaccharide (LPS) showed a reduction in the level of total testosterone in serum, increase of Leydig cell nuclei and the diameters of the convoluted tubules, on the 7 th day, these figures were normalized. The introduction of LPS against giperandrogenemii recorded the most pronounced morphological changes, including significant reduction in the index of spermatogenesis, which reflects the suppression of spermatogenic function.
ISSN:0204-3475
2500-2546
DOI:10.17816/PAVLOVJ201125-5