Comparative study of body fluid cytology using cytocentrifuge and ordinary centrifuge

• Published in: Indian journal of pathology and oncology Vol. 11; no. 1; pp. 14 - 19
• Main Authors: Roy, Madhuri, Wakkar, Darshana
• Format: Journal Article
• Language: English
• Published: 28.04.2024
• ISSN: 2394-6784; 2394-6792
• DOI: 10.18231/j.ijpo.2024.004

The detection of numerous bacterial, fungal, or viral illnesses as well as malignancies is aided by the cytologic study of bodily cavity fluids. The focus of this study is on the type of malignant cells, their distribution and preservation of morphology, cell yield, and comparing the outcomes for positive cases. : To assess the utility, sensitivity and compare the results obtained by cytocentrifuge (Pr0Cyt.LED4) with those of conventional centrifuge in cytodiagnosis in Tertiary Care Hospital. A prospective investigation was carried out using ascitic, pleural, cerebrospinal, and other bodily cavity fluid samples that were split equally and centrifuged simultaneously at predetermined parameters in an ordinary centrifuge and a cytocentrifuge. For cytodiagnosis, 100 samples were examined. With a p-value less than 0.05, the results demonstrated a statistically significant difference between the two approaches. According to this comparison study, the cytocentrifuge preparation outperforms the ordinary centrifuge in terms of cell yield, well-preserved cell morphology, and ability to pick up malignant cells, hence enhancing its sensitivity and improving its diagnostic use.