Ultrasound-guided intraglandular botulinum toxin A injections in the treatment of sialorrhea in pediatric patients

• Published in: Praxis of Otorhinolaryngology Vol. 10; no. 3; pp. 121 - 125
• Main Author: Gergin, Özgül
• Format: Journal Article
• Language: English
• Published: 27.10.2022
• ISSN: 2587-0408; 2587-0408
• DOI: 10.5606/kbbu.2022.30932

Objectives: The objective of this study was to present our experience and evaluate our results of botulinum toxin A (BTX-A) injection applied to major salivary glands in children with sialorrhea. Patients and Methods: Seventeen pediatric patients (11 males, 6 females; mean age: 9.6±4.5 years; range, 4 to 17 years) who underwent BTX-A injection were included in the study. The severity of complaints about sialorrhea of the patients was evaluated using the Sialorrhea Frequency and Severity Assessment Score (DFSS). The scoring was completed by the parents before the procedure and at the first, third, and sixth month after the procedure. Whether there was a difference between the short-and long-term scores after the BTX-A injection was investigated. Results: When the pretreatment DFSS was compared with the scores at the first, third, and sixth months after treatment, it was observed that all posttreatment scores were statistically significantly lower than before the treatment (p<0.05). It was observed that the sixth month scores after the treatment were statistically significantly higher than the first and third month scores (p<0.05). However, there was no statistically significant difference between the first and third month scores after treatment (p>0.05). Conclusion: In our study, BTX-A injection to bilateral parotid and submandibular glands was shown to be an effective method in children with symptoms of sialorrhea.