TCD study of hemodynamic changes in PCA response to photic stimulation

• Published in: Journal of Zhejiang University. Science Vol. 4; no. 2; pp. 228 - 231
• Main Author: 郑旭宁 朱雄超 徐秋芳 黄一宁 柳扬
• Format: Journal Article
• Language: English
• Published: China 01.03.2003
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Diabetes Complications; Diabetes Mellitus - physiopathology; Female; Heart Rate; Hemodynamics; Humans; Hypertension - complications; Hypertension - physiopathology; Male; Middle Aged; Photic Stimulation; Posterior Cerebral Artery - diagnostic imaging; Posterior Cerebral Artery - physiopathology; Statistics as Topic; Ultrasonography, Doppler, Transcranial - methods; 光刺激反应; 大脑后动脉; 血流速度; 血液动力学; 血管收缩反应; 颅侧多普勒效应
• ISSN: 1009-3095

Obiectives:During visual stimulation,the elevated metabolism rate will couple wity increase of blood flow velocity(BFV) in posterior cerebral artery(PCA),This strudy with TCD was aimed to investigate whether the coupling might change according to the different vasoneuronal conditions.Methods:Ninety-nine volunteers including 24 hypertension(HT) patients and 2 patients suffering from both HT and diabetes mellitus (DM) were enrolled in this trial.BFV and pulse indexes(PI) in P2 segments of PCA on both sides were mon-itored during visual stimulation.Results:In all subjects,Mean BFV increased and PI went down in response to visual stimulation.The percentages of changtes(△V and △P) of both mean BFV and PI were larger in young group(<55 years old)than in old one(≥55 years old),There was significant positive correlation be-tween △V and △P.Multivariated regression analysis did not show HT and DM,but age related to △V(△P).We did not find significant difference of △V(△P) between left and right sides,Conclusions:Blood flow ve-locity in PCA P2 segment increased due to decreased cerebrovascular resistance during visual stimulation and the response weakened with aging of the patient.