Successful treatment of neuro-Behçet’s disease with infliximab: four years follow-up

Neuro-Behçet’s disease (NBD) is a rare but severe manifestation of Behçet’s disease. Patients with NBD tend to have high morbidity and mortality. Some patients do not respond adequately to conventional therapy (corticosteroids and immunosuppressants). This has led to treatment gaps in the therapy...

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Published inRheumatology reports Vol. 7; no. 1
Main Authors Kaur, Manjinder, Nia, Emily S., Millius, Rebecca A., Sudano, Dominick G., Lisse, Jeffrey R.
Format Journal Article
LanguageEnglish
Published 20.10.2015
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Summary:Neuro-Behçet’s disease (NBD) is a rare but severe manifestation of Behçet’s disease. Patients with NBD tend to have high morbidity and mortality. Some patients do not respond adequately to conventional therapy (corticosteroids and immunosuppressants). This has led to treatment gaps in the therapy of NBD. There are reports in the literature of patients with Behçet’s disease responding to anti-TNF therapy. We present a case of a male patient with biopsy proven cerebral vasculitis presenting as NBD who has been in remission with near resolution of cerebral magnetic resonance imaging lesions for 4 years following treatment with infliximab and azathioprine.
ISSN:2036-7511
2036-752X
DOI:10.4081/rr.2015.6115