European H16N3 gull influenza virus attaches to the human respiratory tract and eye
We explored the attachment of an H16N3 influenza virus to human, mallard, and gull tissues using virus histochemistry applied to tissue microarrays and employing human and mallard viruses as references. Of the viruses tested, the H16N3 gull virus most readily attached to the human respiratory tract...
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Published in | PloS one Vol. 8; no. 4; p. e60757 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Public Library of Science
08.04.2013
Public Library of Science (PLoS) |
Subjects | |
Online Access | Get full text |
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Summary: | We explored the attachment of an H16N3 influenza virus to human, mallard, and gull tissues using virus histochemistry applied to tissue microarrays and employing human and mallard viruses as references. Of the viruses tested, the H16N3 gull virus most readily attached to the human respiratory tract and eye. These results underscore the need to assess the potential for gull influenza viruses to replicate in human tissues and further investigate the role of gulls in influenza virus ecology. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Competing Interests: The authors have declared that no competing interests exist. Obtained permissions for tissue sampling: FP PE BO DGA. Conceived and designed the experiments: EJ PE BO. Performed the experiments: CL EJ. Analyzed the data: CL EJ PE DvR. Contributed reagents/materials/analysis tools: FP PE BO VM TK DGA. Wrote the paper: EJ CL PE DvR VM TK. |
ISSN: | 1932-6203 1932-6203 |
DOI: | 10.1371/journal.pone.0060757 |