A proposed classification of the immunological diseases

The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive immunity.

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Bibliographic Details
Published inPLoS medicine Vol. 3; no. 8; p. e297
Main Authors McGonagle, Dennis, McDermott, Michael F
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 01.08.2006
Public Library of Science (PLoS)
Subjects
Antigens
Arthritis
Arthritis, Psoriatic - immunology
Autoimmune diseases
Autoimmunity - genetics
Autoimmunity - immunology
Charitable foundations
Classification
Disease
Fever
Humans
Immune system
Immune System Diseases - classification
Immune System Diseases - therapy
Immunologic diseases
Immunology
Immunology and allergy
Immunology/Allergy and Hypersensitivity
Inflammation
Inflammation - genetics
Inflammation - immunology
Mutation
Pharmacology
Public Health and Epidemiology
Research in Translation
Rheumatoid arthritis
Rheumatology
Systemic Lupus Erythematosus
Tumor necrosis factor-TNF
United States
Autoimmunity
Immune System Diseases
Inflammation
Arthritis, Psoriatic
Humans
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Summary:The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive immunity.
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Dennis McGonagle is Professor of Investigative Rheumatology, and Michael F. McDermott is Professor of Experimental Rheumatology, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, United Kingdom.
The authors declare that they have no competing interests.
ISSN:1549-1676
1549-1277
1549-1676
DOI:10.1371/journal.pmed.0030297