Nerve conduction study of median nerve with severity of airway obstruction

• Published in: National journal of physiology, pharmacy and pharmacology Vol. 9; no. 6; pp. 1 - 539
• Main Authors: Shrivastava, Sanjeev, Dave, Rashmi, Shrivastava, Asha
• Format: Journal Article
• Language: English
• Published: Surat Association of Physiologists, Pharmacists & Pharmacologists 2019
• Subjects: Airway management; Chronic obstructive pulmonary disease; Gases; Illnesses; Inflammation; Lungs; Metabolism; Peripheral neuropathy; Quality of life; Smoking
• ISSN: 2320-4672; 2231-3206
• DOI: 10.5455/njppp.2019.9.0311328032019

Chronic Obstructive Pulmonary Disease; Hypoxemia; Demyelination INTRODUCTION Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease characterized by airflow limitation which is usually progressive and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarette smoking. Destruction of lung tissue occurs due to increase in proliferation of the structural cells along with increased apoptotic alveolar epithelial (vascular endothelial cell growth factor, caspase-3, and ceramide) and endothelial cells result in and the development of emphysema, pro-inflammatory chemokines, and cytokines into the circulation marks the development of extrapulmonary manifestation. [7] The airway lumen is reduced due to mural inflammation of small airways and airways remodeling. [...]combination of airways inflammation and remodeling, bronchospasm, mucous hypersecretion, and loss of elastic recoil cause inflammation of small airways and airways remodeling. Exclusion Criteria The following criteria were excluded from the study: * Very severe grade of COPD patients with comorbidities. * Patients with asthma, recent myocardial infarction or unstable angina, endocrinal, and metabolic or renal disorder. * History of neurotoxic drugs or pre-diagnosed peripheral neuropathy.