Altered Functional Connectivity and Small-World in Mesial Temporal Lobe Epilepsy

• Published in: PloS one Vol. 5; no. 1; p. e8525
• Main Authors: Liao, Wei, Zhang, Zhiqiang, Pan, Zhengyong, Mantini, Dante, Ding, Jurong, Duan, Xujun, Luo, Cheng, Lu, Guangming, Chen, Huafu
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.01.2010; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Alterations; Alzheimer's disease; Alzheimers disease; Brain; Brain architecture; Brain mapping; Brain research; Case-Control Studies; Clustering; Computational Biology/Computational Neuroscience; Computational Biology/Signaling Networks; Correlation analysis; Cortex; Education; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe - physiopathology; Female; Functional magnetic resonance imaging; Humans; Hypotheses; Laboratories; Life sciences; Lobes; Magnetic resonance; Magnetic Resonance Imaging; Male; Medical imaging; Mental disorders; Middle Aged; Neural networks; Neuroimaging; Neurons; Neuroscience; Patients; Properties (attributes); Radiology and Medical Imaging/Magnetic Resonance Imaging; Studies; Temporal lobe; Temporal lobe epilepsy; Young Adult; Italy; China

The functional architecture of the human brain has been extensively described in terms of functional connectivity networks, detected from the low-frequency coherent neuronal fluctuations that can be observed in a resting state condition. Little is known, so far, about the changes in functional conne...