Novel method to analyze cell kinetics for the rapid diagnosis and determination of the causative agent in allergy

• Published in: PLOS ONE Vol. 16; no. 2; p. e0246125
• Main Authors: Shibaguchi, Hirotomo, Yasutaka, Yuki, Futagami, Koujiro
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science (PLoS) 19.02.2021; Public Library of Science
• Subjects: Allergens; Allergies; Allergy; Antigens; Biochemistry; Biology and Life Sciences; Case-Control Studies; Causes of; Cell adhesion & migration; Cell Movement; Chemokines; Chemotactic Factors; Computer and Information Sciences; Cytodiagnosis; Cytokines; Diagnosis; Dose-Response Relationship, Drug; Drug allergy; Drug Hypersensitivity; Early Diagnosis; Editing; Engineering and Technology; Flow Cytometry; Funding; Genetic screening; Granulocytes; Health care; Histocompatibility antigen HLA; Hospitals; Humans; Hypersensitivity; Inflammation; Jurkat Cells; Leukocytes; Lymphocytes; Medical diagnosis; Medicine; Medicine and Health Sciences; Metabolites; Methods; Patients; Pharmaceutical sciences; Pharmaceuticals; Pharmacy; Q; R; Rhinitis, Allergic, Seasonal; Science; Sensitivity and Specificity; Testing; Time Factors; Japan; United States > US

Drug-induced allergy (DIA), an unexpectedly triggered side effect of drugs used for therapeutic purposes, is a serious clinical issue that needs to be resolved because it interrupts the treatment of the primary disease. Since conventional allergy testing is insufficient to accurately predict the occ...